A 1 R confocal microscope (Nikon)
The Nikon A1R Confocal Microscope is an advanced laser-scanning system designed for high-resolution, high-speed, and live-cell imaging. Featuring a resonant scanner capable of capturing up to 720 frames per second, it enables real-time visualization of dynamic cellular processes with minimal phototoxicity. Built on the fully motorized Nikon Ti2E inverted microscope, it integrates the Perfect Focus System (PFS) for real-time focus stabilization, ensuring precise long-term imaging. High-sensitivity GaAsP detectors enhance signal-to-noise ratio, enabling deep tissue imaging and improved fluorescence detection. With 405, 488, 561, and 640 nm laser lines, the system supports multi-channel fluorescence imaging with superior spectral separation. Additional capabilities include multiphoton imaging for deep tissue penetration and an incubation chamber for controlled live-cell experiments. Powered by NIS Elements software, it enables multi-dimensional imaging, real-time deconvolution, automated analysis, and 3D reconstruction, making it an essential tool for applications in cell biology, neuroscience, cancer research, and advanced fluorescence imaging.
The Alexander Silberman Institute of Life Science | Site
Edmond J. Safra (Givat-Ram)
Bio-Imaging Unit
Contacts
- Naomi Melamed-Book
- book@mail.huji.ac.il